Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice

Deficiency of glucose-6-phosphate dehydrogenase (G6PD) is the single most common enzymopathy, present in approximately 400 million humans (approximately 5%). Its prevalence is hypothesized to be due to conferring resistance to malaria. However, G6PD deficiency also results in hemolytic sequelae from...

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Detalles Bibliográficos
Autores principales: D’Alessandro, Angelo, Howie, Heather L., Hay, Ariel M., Dziewulska, Karolina H., Brown, Benjamin C., Wither, Matthew J., Karafin, Matthew, Stone, Elizabeth F., Spitalnik, Steven L., Hod, Eldad A., Francis, Richard O., Fu, Xiaoyun, Thomas, Tiffany, Zimring, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410095/
https://www.ncbi.nlm.nih.gov/pubmed/34138756
http://dx.doi.org/10.1172/jci.insight.147056

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