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Potential Achilles heels of SARS-CoV-2 are best displayed by the base order-dependent component of RNA folding energy

The base order-dependent component of folding energy has revealed a highly conserved region in HIV-1 genomes that associates with RNA structure. This corresponds to a packaging signal that is recognized by the nucleocapsid domain of the Gag polyprotein. Long viewed as a potential HIV-1 "Achille...

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Detalles Bibliográficos
Autores principales: Zhang, Chiyu, Forsdyke, Donald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410225/
https://www.ncbi.nlm.nih.gov/pubmed/34500325
http://dx.doi.org/10.1016/j.compbiolchem.2021.107570