Characterization of fragment sizes, copy number aberrations and 4‐mer end motifs in cell‐free DNA of hepatocellular carcinoma for enhanced liquid biopsy‐based cancer detection

Circulating cell‐free DNA (cfDNA) fragmentomics, which encompasses the measurement of cfDNA length and short nucleotide motifs at the ends of cfDNA molecules, is an emerging field for cancer diagnosis. The utilization of cfDNA fragmentomics for the diagnosis of patients with hepatocellular carcinoma...

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Detalles Bibliográficos
Autores principales: Jin, Chao, Liu, Xiaonan, Zheng, Wenyuan, Su, Liping, Liu, Yang, Guo, Xu, Gu, Xiaoming, Li, Hongping, Xu, Bo, Wang, Gang, Yu, Jiyan, Zhang, Qiong, Bao, Dengke, Wan, Shaogui, Xu, Fei, Lai, Xiaohuan, Liu, Jiayun, Xing, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410516/
https://www.ncbi.nlm.nih.gov/pubmed/34133846
http://dx.doi.org/10.1002/1878-0261.13041

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