CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition

The intestine‐specific caudal‐related homeobox gene‐2 (CDX2) homeobox gene, while being a tumor suppressor in the gut, is ectopically expressed in a large proportion of acute leukemia and is associated with poor prognosis. Here, we report that turning on human CDX2 expression in the hematopoietic li...

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Detalles Bibliográficos
Autores principales: Galland, Ava, Gourain, Victor, Habbas, Karima, Güler, Yonca, Martin, Elisabeth, Ebel, Claudine, Tavian, Manuela, Vallat, Laurent, Chenard, Marie‐Pierre, Mauvieux, Laurent, Freund, Jean‐Noël, Duluc, Isabelle, Domon‐Dell, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410536/
https://www.ncbi.nlm.nih.gov/pubmed/33960108
http://dx.doi.org/10.1002/1878-0261.12982

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