FLT3‐ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation

Recurrent somatic internal tandem duplications (ITD) in the FMS‐like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3‐ITD mutation status guides risk‐adapted treatment strategies. The aim of this work was to characterise FLT3...

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Detalles Bibliográficos
Autores principales: Engen, Caroline, Hellesøy, Monica, Grob, Tim, Al Hinai, Adil, Brendehaug, Atle, Wergeland, Line, Bedringaas, Siv Lise, Hovland, Randi, Valk, Peter J. M., Gjertsen, Bjørn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410560/
https://www.ncbi.nlm.nih.gov/pubmed/33817952
http://dx.doi.org/10.1002/1878-0261.12961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410560/
https://www.ncbi.nlm.nih.gov/pubmed/33817952
http://dx.doi.org/10.1002/1878-0261.12961

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