FLT3‐ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation

Recurrent somatic internal tandem duplications (ITD) in the FMS‐like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3‐ITD mutation status guides risk‐adapted treatment strategies. The aim of this work was to characterise FLT3...

Descripción completa

Detalles Bibliográficos
Autores principales: Engen, Caroline, Hellesøy, Monica, Grob, Tim, Al Hinai, Adil, Brendehaug, Atle, Wergeland, Line, Bedringaas, Siv Lise, Hovland, Randi, Valk, Peter J. M., Gjertsen, Bjørn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410560/
https://www.ncbi.nlm.nih.gov/pubmed/33817952
http://dx.doi.org/10.1002/1878-0261.12961

Ejemplares similares

Ejemplares similares