BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma

Richter Transformation (RT) develops in CLL as an aggressive, therapy-resistant, diffuse large B cell lymphoma (RT-DLBCL), commonly clonally-related (CLR) to the concomitant CLL. Lack of available pre-clinical human models has hampered the development of novel therapies for RT-DLBCL. Here, we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Fiskus, Warren, Mill, Christopher P., Perera, Dimuthu, Birdwell, Christine, Deng, Qing, Yang, Haopeng, Lara, Bernardo H., Jain, Nitin, Burger, Jan, Ferrajoli, Alessandra, Davis, John A., Saenz, Dyana T., Jin, Wendy, Coarfa, Cristian, Crews, Craig M., Green, Michael R., Khoury, Joseph D., Bhalla, Kapil N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410602/
https://www.ncbi.nlm.nih.gov/pubmed/33654205
http://dx.doi.org/10.1038/s41375-021-01181-w

Ejemplares similares

Ejemplares similares