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Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities
OBJECTIVE: We investigated cancer survivors’ health-related quality of life (HRQOL), specific deficiencies related to underlying disease or treatment, and benefits of rehabilitation in a large variety of cancer entities. PATIENTS AND METHODS: Electronic patient-reported outcomes were performed as cl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410699/ https://www.ncbi.nlm.nih.gov/pubmed/33755805 http://dx.doi.org/10.1007/s00520-021-06123-x |
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author | Licht, Thomas Nickels, Alain Rumpold, Gerhard Holzner, Bernhard Riedl, David |
author_facet | Licht, Thomas Nickels, Alain Rumpold, Gerhard Holzner, Bernhard Riedl, David |
author_sort | Licht, Thomas |
collection | PubMed |
description | OBJECTIVE: We investigated cancer survivors’ health-related quality of life (HRQOL), specific deficiencies related to underlying disease or treatment, and benefits of rehabilitation in a large variety of cancer entities. PATIENTS AND METHODS: Electronic patient-reported outcomes were performed as clinical routine procedures. Cancer survivors underwent a 3-week multidisciplinary inpatient rehabilitation. Twenty-one different cancer entities were analyzed separately before (T0) and by the end (T1) of rehabilitation. HRQOL, symptoms, and functions were assessed with EORTC-QLQ-C30 questionnaire, psychological distress with Hospital Anxiety and Depression Scale (HADS). RESULTS: Four thousand four hundred one of 5912 rehabilitants were evaluable, having completed both questionnaires at T0 and T1. All function mean scores and HRQOL were lower than in Austrian normal population, while levels of anxiety, depression, and all symptom scores were higher. HRQOL was particularly low in lung, liver, and bladder cancer patients. Maximum anxiety levels were observed in patients with breast and thyroid cancer patients, the highest levels of depression in liver and brain cancer patients. Fatigue was severe in patients with lung, liver, esophageal, bladder cancer, and myeloma patients. Mean scores were also high for pain and insomnia. In the group of all rehabilitants, a highly significant improvement of global HRQOL, anxiety, depression, and all function and symptom scores was observed at T1 (p < 0.001). We noted significant improvement of HRQOL, anxiety, depression, fatigue, emotional, social, role, and physical functions in each cancer entity with medium to large effect sizes. Other recorded symptoms were reduced in the majority of cancers. CONCLUSION: Rehabilitation effectively improves psychological distress and HRQOL as a part of treatment for various cancers. |
format | Online Article Text |
id | pubmed-8410699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-84106992021-09-22 Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities Licht, Thomas Nickels, Alain Rumpold, Gerhard Holzner, Bernhard Riedl, David Support Care Cancer Original Article OBJECTIVE: We investigated cancer survivors’ health-related quality of life (HRQOL), specific deficiencies related to underlying disease or treatment, and benefits of rehabilitation in a large variety of cancer entities. PATIENTS AND METHODS: Electronic patient-reported outcomes were performed as clinical routine procedures. Cancer survivors underwent a 3-week multidisciplinary inpatient rehabilitation. Twenty-one different cancer entities were analyzed separately before (T0) and by the end (T1) of rehabilitation. HRQOL, symptoms, and functions were assessed with EORTC-QLQ-C30 questionnaire, psychological distress with Hospital Anxiety and Depression Scale (HADS). RESULTS: Four thousand four hundred one of 5912 rehabilitants were evaluable, having completed both questionnaires at T0 and T1. All function mean scores and HRQOL were lower than in Austrian normal population, while levels of anxiety, depression, and all symptom scores were higher. HRQOL was particularly low in lung, liver, and bladder cancer patients. Maximum anxiety levels were observed in patients with breast and thyroid cancer patients, the highest levels of depression in liver and brain cancer patients. Fatigue was severe in patients with lung, liver, esophageal, bladder cancer, and myeloma patients. Mean scores were also high for pain and insomnia. In the group of all rehabilitants, a highly significant improvement of global HRQOL, anxiety, depression, and all function and symptom scores was observed at T1 (p < 0.001). We noted significant improvement of HRQOL, anxiety, depression, fatigue, emotional, social, role, and physical functions in each cancer entity with medium to large effect sizes. Other recorded symptoms were reduced in the majority of cancers. CONCLUSION: Rehabilitation effectively improves psychological distress and HRQOL as a part of treatment for various cancers. Springer Berlin Heidelberg 2021-03-23 2021 /pmc/articles/PMC8410699/ /pubmed/33755805 http://dx.doi.org/10.1007/s00520-021-06123-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Licht, Thomas Nickels, Alain Rumpold, Gerhard Holzner, Bernhard Riedl, David Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title | Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title_full | Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title_fullStr | Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title_full_unstemmed | Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title_short | Evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
title_sort | evaluation by electronic patient-reported outcomes of cancer survivors’ needs and the efficacy of inpatient cancer rehabilitation in different tumor entities |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410699/ https://www.ncbi.nlm.nih.gov/pubmed/33755805 http://dx.doi.org/10.1007/s00520-021-06123-x |
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