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Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer’s Disease

PURPOSE: The triggering receptor expressed on myeloid cells 2 (TREM2) is expressed by brain microglia. Microglial activation, as observed in Alzheimer’s disease (AD) as well as in transgenic mice expressing human amyloid-beta, appears to increase soluble TREM2 (sTREM2) levels in CSF and brain. In th...

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Detalles Bibliográficos
Autores principales:	Meier, Silvio R., Sehlin, Dag, Hultqvist, Greta, Syvänen, Stina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410720/ https://www.ncbi.nlm.nih.gov/pubmed/33620643 http://dx.doi.org/10.1007/s11307-021-01591-3

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