Cargando…

A CDK-regulated chromatin segregase promoting chromosome replication

The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can result in genome instability, which is a major driver of cancer. Yet how chromatin is made accessible during eukaryotic DNA synthesis is poorly understood. Here, we report the chara...

Descripción completa

Detalles Bibliográficos
Autores principales: Chacin, Erika, Bansal, Priyanka, Reusswig, Karl-Uwe, Diaz-Santin, Luis M., Ortega, Pedro, Vizjak, Petra, Gómez-González, Belen, Müller-Planitz, Felix, Aguilera, Andrés, Pfander, Boris, Cheung, Alan C. M., Kurat, Christoph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410769/
https://www.ncbi.nlm.nih.gov/pubmed/34471130
http://dx.doi.org/10.1038/s41467-021-25424-7