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A CDK-regulated chromatin segregase promoting chromosome replication
The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can result in genome instability, which is a major driver of cancer. Yet how chromatin is made accessible during eukaryotic DNA synthesis is poorly understood. Here, we report the chara...
Autores principales: | Chacin, Erika, Bansal, Priyanka, Reusswig, Karl-Uwe, Diaz-Santin, Luis M., Ortega, Pedro, Vizjak, Petra, Gómez-González, Belen, Müller-Planitz, Felix, Aguilera, Andrés, Pfander, Boris, Cheung, Alan C. M., Kurat, Christoph F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410769/ https://www.ncbi.nlm.nih.gov/pubmed/34471130 http://dx.doi.org/10.1038/s41467-021-25424-7 |
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