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Naloxone precipitated withdrawal increases dopamine release in the dorsal striatum of opioid dependent men
Dopamine (DA) neurotransmission is critical in the neurobiology of reward and aversion, but its contribution to the aversive state of opioid withdrawal remains unknown in humans. To address this, we used updated voxelwise methods and retrospectively analyzed a [(11)C]raclopride-PET dataset to measur...
Autores principales: | Shokri-Kojori, Ehsan, Wang, Gene-Jack, Volkow, Nora D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410787/ https://www.ncbi.nlm.nih.gov/pubmed/34471102 http://dx.doi.org/10.1038/s41398-021-01548-8 |
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