Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia

Molecular mechanisms associated with human germ cell aplasia in infertile men remain undefined. Here we perform single-cell transcriptome profiling to highlight differentially expressed genes and pathways in each somatic cell type in testes of men with idiopathic germ cell aplasia. We identify immat...

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Detalles Bibliográficos
Autores principales: Alfano, Massimo, Tascini, Anna Sofia, Pederzoli, Filippo, Locatelli, Irene, Nebuloni, Manuela, Giannese, Francesca, Garcia-Manteiga, Jose Manuel, Tonon, Giovanni, Amodio, Giada, Gregori, Silvia, Agresti, Alessandra, Montorsi, Francesco, Salonia, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410861/
https://www.ncbi.nlm.nih.gov/pubmed/34471128
http://dx.doi.org/10.1038/s41467-021-25544-0

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