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Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke

BACKGROUND: Neonatal stroke affects 1 in 2800 live births and is a major cause of neurological injury. The Sonic hedgehog (Shh) signaling pathway is critical for central nervous system (CNS) development and has neuroprotective and reparative effects in different CNS injury models. Previous studies h...

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Detalles Bibliográficos
Autores principales: Nguyen, Vien, Chavali, Manideep, Larpthaveesarp, Amara, Kodali, Srikirti, Gonzalez, Ginez, Franklin, Robin J. M., Rowitch, David H., Gonzalez, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410885/
https://www.ncbi.nlm.nih.gov/pubmed/33654279
http://dx.doi.org/10.1038/s41390-021-01408-7

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