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Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke
BACKGROUND: Neonatal stroke affects 1 in 2800 live births and is a major cause of neurological injury. The Sonic hedgehog (Shh) signaling pathway is critical for central nervous system (CNS) development and has neuroprotective and reparative effects in different CNS injury models. Previous studies h...
Autores principales: | Nguyen, Vien, Chavali, Manideep, Larpthaveesarp, Amara, Kodali, Srikirti, Gonzalez, Ginez, Franklin, Robin J. M., Rowitch, David H., Gonzalez, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410885/ https://www.ncbi.nlm.nih.gov/pubmed/33654279 http://dx.doi.org/10.1038/s41390-021-01408-7 |
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