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[(18)F]-AV-1451 binding in the substantia nigra as a marker of neuromelanin in Lewy body diseases
While [(18)F]-AV-1451 was developed as a PET radiotracer with high affinity for hyperphosphorylated tau, it has been proposed that loss of ‘off-target’ [(18)F]-AV-1451 binding to neuromelanin in the substantia nigra could be a surrogate marker of Lewy body diseases. [(18)F]-AV-1451 binding was measu...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410984/ https://www.ncbi.nlm.nih.gov/pubmed/34485906 http://dx.doi.org/10.1093/braincomms/fcab177 |