Cargando…
A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells
Lung-resident memory T cells (T(RM)) play an essential role in protecting against pulmonary virus infection. Parenteral administration of DNA vaccine is generally not sufficient to induce lung CD8 T(RM) cells. This study investigates whether intramuscularly administered DNA vaccine expressing the nu...
Autores principales: | Chung, Haerynn, Kim, Eun-Ah, Chang, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410988/ https://www.ncbi.nlm.nih.gov/pubmed/34522441 http://dx.doi.org/10.4110/in.2021.21.e28 |
Ejemplares similares
-
OVX836 Heptameric Nucleoprotein Vaccine Generates Lung Tissue-Resident Memory CD8+ T-Cells for Cross-Protection Against Influenza
por: Del Campo, Judith, et al.
Publicado: (2021) -
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection
por: Kong, Hyun-Jung, et al.
Publicado: (2023) -
Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8(+) T Cells
por: Enamorado, Michel, et al.
Publicado: (2018) -
Control of mucosal virus infection by influenza nucleoprotein-specific CD8(+ )cytotoxic T lymphocytes
por: Mbawuike, Innocent N, et al.
Publicado: (2007) -
Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein
por: Luo, Jian, et al.
Publicado: (2012)