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A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells

Lung-resident memory T cells (T(RM)) play an essential role in protecting against pulmonary virus infection. Parenteral administration of DNA vaccine is generally not sufficient to induce lung CD8 T(RM) cells. This study investigates whether intramuscularly administered DNA vaccine expressing the nu...

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Detalles Bibliográficos
Autores principales: Chung, Haerynn, Kim, Eun-Ah, Chang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410988/
https://www.ncbi.nlm.nih.gov/pubmed/34522441
http://dx.doi.org/10.4110/in.2021.21.e28

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