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Suppressive Effect of CYM50358 S1P(4) Antagonist on Mast Cell Degranulation and Allergic Asthma in Mice
Levels of sphingosine 1-phosphate (S1P), an intercellular signaling molecule, reportedly increase in the bronchoalveolar lavage fluids of patients with asthma. Although the type 4 S1P receptor, S1P(4) has been detected in mast cells, its functions have been poorly investigated in an allergic asthma...
Autores principales: | Jeon, Wi-Jin, Chung, Ki Wung, Lee, Joon-Hee, Im, Dong-Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411020/ https://www.ncbi.nlm.nih.gov/pubmed/33500376 http://dx.doi.org/10.4062/biomolther.2020.206 |
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