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Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice

Parkinson’s disease (PD) is a neurodegenerative disorder that involves the loss of dopaminergic neurons in the substantia nigra (SN). Matrix metalloproteinases-8 (MMP-8), neutrophil collagenase, is a functional player in the progressive pathology of various inflammatory disorders. In this study, we...

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Detalles Bibliográficos
Autores principales: Kim, Taewoo, Jeon, Jeha, Park, Jin-Sun, Park, Yeongwon, Kim, Jooeui, Noh, Haneul, Kim, Hee-Sun, Seo, Hyemyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411029/
https://www.ncbi.nlm.nih.gov/pubmed/34045367
http://dx.doi.org/10.4062/biomolther.2020.181