Cargando…
Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice
Parkinson’s disease (PD) is a neurodegenerative disorder that involves the loss of dopaminergic neurons in the substantia nigra (SN). Matrix metalloproteinases-8 (MMP-8), neutrophil collagenase, is a functional player in the progressive pathology of various inflammatory disorders. In this study, we...
Autores principales: | Kim, Taewoo, Jeon, Jeha, Park, Jin-Sun, Park, Yeongwon, Kim, Jooeui, Noh, Haneul, Kim, Hee-Sun, Seo, Hyemyung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411029/ https://www.ncbi.nlm.nih.gov/pubmed/34045367 http://dx.doi.org/10.4062/biomolther.2020.181 |
Ejemplares similares
-
HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice
por: Kim, Taewoo, et al.
Publicado: (2019) -
LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25
por: Yun, Hye Jin, et al.
Publicado: (2013) -
The G2019S LRRK2 Mutation is Rare in Korean Patients with Parkinson's Disease and Multiple System Atrophy
por: Cho, Jin-Whan, et al.
Publicado: (2009) -
Prediction of miRNA-mRNA associations in Alzheimer’s disease mice using network topology
por: Noh, Haneul, et al.
Publicado: (2014) -
Age-associated chromatin relaxation is enhanced in Huntington's disease mice
por: Park, Myungsun, et al.
Publicado: (2017)