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Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer

The imprinted tumour suppressor NOEY2 is downregulated in various cancer types, including ovarian cancers. Recent data suggest that NOEY2 plays an essential role in regulating the cell cycle, angiogenesis and autophagy in tumorigenesis. However, its detailed molecular function and mechanisms in ovar...

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Detalles Bibliográficos
Autores principales: Rho, Seung Bae, Lee, Keun Woo, Lee, Seung-Hoon, Byun, Hyun Jung, Kim, Boh-Ram, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411030/
https://www.ncbi.nlm.nih.gov/pubmed/34462379
http://dx.doi.org/10.4062/biomolther.2021.121