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Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections

Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. The Carnivora, like mink, carry many zoonoses, yet how diversity in host immune genes across species affect pathogen carriage is poorly understood. Here, we describe a progressive evolutionary downr...

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Detalles Bibliográficos
Autores principales: Digby, Zsofi, Tourlomousis, Panagiotis, Rooney, James, Boyle, Joseph P., Bibo-Verdugo, Betsaida, Pickering, Robert J., Webster, Steven J., Monie, Thomas P., Hopkins, Lee J., Kayagaki, Nobuhiko, Salvesen, Guy S., Warming, Soren, Weinert, Lucy, Bryant, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411117/
https://www.ncbi.nlm.nih.gov/pubmed/34433041
http://dx.doi.org/10.1016/j.celrep.2021.109614