Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells

T cell engineering strategies offer cures to patients and have entered clinical practice with chimeric antibody-based receptors; αβT cell receptor (αβTCR)-based strategies are, however, lagging behind. To allow a more rapid and successful translation to successful concepts also using αβTCRs for engi...

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Detalles Bibliográficos
Autores principales: Kierkels, Guido J.J., van Diest, Eline, Hernández-López, Patricia, Scheper, Wouter, de Bruin, Anja C.M., Frijlink, Elselien, Aarts-Riemens, Tineke, van Dooremalen, Sanne F.J., Beringer, Dennis X., Oostvogels, Rimke, Kramer, Lovro, Straetemans, Trudy, Uckert, Wolfgang, Sebestyén, Zsolt, Kuball, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411211/
https://www.ncbi.nlm.nih.gov/pubmed/34514030
http://dx.doi.org/10.1016/j.omtm.2021.06.011

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