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Modeling the impact of early interventions on the transmission dynamics of coronavirus infection

A deterministic model is proposed to describe the transmission dynamics of coronavirus infection with early interventions. Epidemiological studies have employed modeling to unravel knowledge that transformed the lives of families, communities, nations and the entire globe. The study established the...

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Detalles Bibliográficos
Autores principales: Bornaa, Christopher Saaha, Seidu, Baba, Seini, Yakubu Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411273/
https://www.ncbi.nlm.nih.gov/pubmed/34527217
http://dx.doi.org/10.12688/f1000research.54268.2
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author Bornaa, Christopher Saaha
Seidu, Baba
Seini, Yakubu Ibrahim
author_facet Bornaa, Christopher Saaha
Seidu, Baba
Seini, Yakubu Ibrahim
author_sort Bornaa, Christopher Saaha
collection PubMed
description A deterministic model is proposed to describe the transmission dynamics of coronavirus infection with early interventions. Epidemiological studies have employed modeling to unravel knowledge that transformed the lives of families, communities, nations and the entire globe. The study established the stability of both disease free and endemic equilibria. Stability occurs when the reproduction number, R0, is less than unity for both disease free and endemic equilibrium points. The global stability of the disease-free equilibrium point of the model is established whenever the basic reproduction number R0 is less than or equal to unity. The reproduction number is also shown to be directly related to the transmission probability (β), rate at which latently infected individuals join the infected class (δ) and rate of recruitment (Λ). It is inversely related to natural death rate (μ), rate of early treatment (τ (1)), rate of hospitalization of infected individuals (θ) and Covid-induced death rate (σ). The analytical results established are confirmed by numerical simulation of the model.
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spelling pubmed-84112732021-09-14 Modeling the impact of early interventions on the transmission dynamics of coronavirus infection Bornaa, Christopher Saaha Seidu, Baba Seini, Yakubu Ibrahim F1000Res Method Article A deterministic model is proposed to describe the transmission dynamics of coronavirus infection with early interventions. Epidemiological studies have employed modeling to unravel knowledge that transformed the lives of families, communities, nations and the entire globe. The study established the stability of both disease free and endemic equilibria. Stability occurs when the reproduction number, R0, is less than unity for both disease free and endemic equilibrium points. The global stability of the disease-free equilibrium point of the model is established whenever the basic reproduction number R0 is less than or equal to unity. The reproduction number is also shown to be directly related to the transmission probability (β), rate at which latently infected individuals join the infected class (δ) and rate of recruitment (Λ). It is inversely related to natural death rate (μ), rate of early treatment (τ (1)), rate of hospitalization of infected individuals (θ) and Covid-induced death rate (σ). The analytical results established are confirmed by numerical simulation of the model. F1000 Research Limited 2021-08-17 /pmc/articles/PMC8411273/ /pubmed/34527217 http://dx.doi.org/10.12688/f1000research.54268.2 Text en Copyright: © 2021 Bornaa CS et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Method Article
Bornaa, Christopher Saaha
Seidu, Baba
Seini, Yakubu Ibrahim
Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title_full Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title_fullStr Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title_full_unstemmed Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title_short Modeling the impact of early interventions on the transmission dynamics of coronavirus infection
title_sort modeling the impact of early interventions on the transmission dynamics of coronavirus infection
topic Method Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411273/
https://www.ncbi.nlm.nih.gov/pubmed/34527217
http://dx.doi.org/10.12688/f1000research.54268.2
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