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Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies

AIMS: We explored the use of pulverized medication as a new method to prevent intentional drug overdose. METHODS: This case study presents data obtained from the medical records of two female patients, aged 19 and 27 years, who presented with schizophrenia and neurodevelopmental disorder, respective...

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Autores principales: Takanobu, Keisuke, Okazaki, Daisuke, Watanabe, Shinya, Mitsui, Nobuyuki, Tanaka, Teruaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411305/
https://www.ncbi.nlm.nih.gov/pubmed/34165255
http://dx.doi.org/10.1002/npr2.12189
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author Takanobu, Keisuke
Okazaki, Daisuke
Watanabe, Shinya
Mitsui, Nobuyuki
Tanaka, Teruaki
author_facet Takanobu, Keisuke
Okazaki, Daisuke
Watanabe, Shinya
Mitsui, Nobuyuki
Tanaka, Teruaki
author_sort Takanobu, Keisuke
collection PubMed
description AIMS: We explored the use of pulverized medication as a new method to prevent intentional drug overdose. METHODS: This case study presents data obtained from the medical records of two female patients, aged 19 and 27 years, who presented with schizophrenia and neurodevelopmental disorder, respectively. Both patients provided written informed consent. Medication was administered to the two patients in powdered form, as opposed to in tablet form, in an attempt to prevent intentional drug overdose. RESULTS: This administration method successfully prevented intentional drug overdose for 3 and 5 years in each case, respectively. However, case‐control or prospective cohort studies are needed to rule out biases, including cognitive bias. CONCLUSION: Pulverizing medication is a simple and effective means of preventing intentional drug overdose by restricting access to the means of suicide, regardless of the type of mental disorder.
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spelling pubmed-84113052021-09-03 Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies Takanobu, Keisuke Okazaki, Daisuke Watanabe, Shinya Mitsui, Nobuyuki Tanaka, Teruaki Neuropsychopharmacol Rep Case Reports AIMS: We explored the use of pulverized medication as a new method to prevent intentional drug overdose. METHODS: This case study presents data obtained from the medical records of two female patients, aged 19 and 27 years, who presented with schizophrenia and neurodevelopmental disorder, respectively. Both patients provided written informed consent. Medication was administered to the two patients in powdered form, as opposed to in tablet form, in an attempt to prevent intentional drug overdose. RESULTS: This administration method successfully prevented intentional drug overdose for 3 and 5 years in each case, respectively. However, case‐control or prospective cohort studies are needed to rule out biases, including cognitive bias. CONCLUSION: Pulverizing medication is a simple and effective means of preventing intentional drug overdose by restricting access to the means of suicide, regardless of the type of mental disorder. John Wiley and Sons Inc. 2021-06-24 /pmc/articles/PMC8411305/ /pubmed/34165255 http://dx.doi.org/10.1002/npr2.12189 Text en © 2021 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Takanobu, Keisuke
Okazaki, Daisuke
Watanabe, Shinya
Mitsui, Nobuyuki
Tanaka, Teruaki
Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title_full Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title_fullStr Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title_full_unstemmed Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title_short Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: Two case studies
title_sort pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: two case studies
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411305/
https://www.ncbi.nlm.nih.gov/pubmed/34165255
http://dx.doi.org/10.1002/npr2.12189
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