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Insights into bioinformatic approaches for repurposing compounds as anti-viral drugs

BACKGROUND: Drug repurposing is a cost-effective strategy to identify drugs with novel effects. We searched for drugs exhibiting inhibitory activity to Herpes Simplex virus 1 (HSV-1). Our strategy utilized gene expression data generated from HSV-1-infected cell cultures which was paired with drug ef...

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Detalles Bibliográficos
Autores principales:	Zheng, Wenxiao, D’Aiuto, Leonardo, Demers, Matthew J, Muralidaran, Vaishali, Wood, Joel A, Wesesky, Maribeth, Chattopadhyay, Ansuman, Nimgaonkar, Vishwajit L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411619/ https://www.ncbi.nlm.nih.gov/pubmed/34463534 http://dx.doi.org/10.1177/20402066211036822

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