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A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis

Oropharyngeal dysphagia is defined as the inability or difficulty to initiate swallowing. It has a wide array of etiologies including structural and neurologic diseases. Myasthenia gravis (MG) is a rare autoimmune condition caused by antibodies against the post-synaptic membranes of the neuromuscula...

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Detalles Bibliográficos
Autores principales: Abudalou, Mohammad, Malkowski, Michael, Robles, Marcel R, Vega, Eduardo A, Slama, Michael C. C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411993/
https://www.ncbi.nlm.nih.gov/pubmed/34513455
http://dx.doi.org/10.7759/cureus.16880
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author Abudalou, Mohammad
Malkowski, Michael
Robles, Marcel R
Vega, Eduardo A
Slama, Michael C. C
author_facet Abudalou, Mohammad
Malkowski, Michael
Robles, Marcel R
Vega, Eduardo A
Slama, Michael C. C
author_sort Abudalou, Mohammad
collection PubMed
description Oropharyngeal dysphagia is defined as the inability or difficulty to initiate swallowing. It has a wide array of etiologies including structural and neurologic diseases. Myasthenia gravis (MG) is a rare autoimmune condition caused by antibodies against the post-synaptic membranes of the neuromuscular junction, leading to fatigable weakness of skeletal muscles. Bulbar symptoms are less prevalent than ocular symptoms or limb weakness but can be particularly morbid. Non-neurologists are more likely to be the first providers to evaluate patients with dysphagia and should be familiar with MG. We report a unique case of newly diagnosed MG with the initial presentation of solid food and liquid dysphagia.
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spelling pubmed-84119932021-09-09 A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis Abudalou, Mohammad Malkowski, Michael Robles, Marcel R Vega, Eduardo A Slama, Michael C. C Cureus Neurology Oropharyngeal dysphagia is defined as the inability or difficulty to initiate swallowing. It has a wide array of etiologies including structural and neurologic diseases. Myasthenia gravis (MG) is a rare autoimmune condition caused by antibodies against the post-synaptic membranes of the neuromuscular junction, leading to fatigable weakness of skeletal muscles. Bulbar symptoms are less prevalent than ocular symptoms or limb weakness but can be particularly morbid. Non-neurologists are more likely to be the first providers to evaluate patients with dysphagia and should be familiar with MG. We report a unique case of newly diagnosed MG with the initial presentation of solid food and liquid dysphagia. Cureus 2021-08-04 /pmc/articles/PMC8411993/ /pubmed/34513455 http://dx.doi.org/10.7759/cureus.16880 Text en Copyright © 2021, Abudalou et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Abudalou, Mohammad
Malkowski, Michael
Robles, Marcel R
Vega, Eduardo A
Slama, Michael C. C
A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title_full A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title_fullStr A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title_full_unstemmed A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title_short A Rare Presentation of a Rare Disease: Oropharyngeal Dysphagia as The Main Manifestation of Myasthenia Gravis
title_sort rare presentation of a rare disease: oropharyngeal dysphagia as the main manifestation of myasthenia gravis
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411993/
https://www.ncbi.nlm.nih.gov/pubmed/34513455
http://dx.doi.org/10.7759/cureus.16880
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