Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma

BACKGROUND: Glioblastomas (GBMs) are the most lethal primary brain tumors. Estrogen receptor β (ESR2/ERβ) function as a tumor suppressor in GBM, however, ERβ expression is commonly suppressed during glioma progression. In this study, we examined whether drugs that reverse epigenetic modifications wi...

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Detalles Bibliográficos
Autores principales: Pratap, Uday P, Sareddy, Gangadhara R, Liu, Zexuan, Venkata, Prabhakar Pitta, Liu, Junhao, Tang, Weiwei, Altwegg, Kristin A, Ebrahimi, Behnam, Li, Xiaonan, Tekmal, Rajeshwar R, Viswanadhapalli, Suryavathi, McHardy, Stanton, Brenner, Andrew J, Vadlamudi, Ratna K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412056/
https://www.ncbi.nlm.nih.gov/pubmed/34485908
http://dx.doi.org/10.1093/noajnl/vdab099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412056/
https://www.ncbi.nlm.nih.gov/pubmed/34485908
http://dx.doi.org/10.1093/noajnl/vdab099

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