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Detection and quantification of novel C‐terminal TDP‐43 fragments in ALS‐TDP

The pathological hallmark of amyotrophic lateral sclerosis (ALS) is the presence of cytoplasmic inclusions, containing C‐terminal fragments of the protein TDP‐43. Here, we tested the hypothesis that highly sensitive mass spectrometry with parallel reaction monitoring (MS‐PRM) can generate a high‐res...

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Detalles Bibliográficos
Autores principales:	Feneberg, Emily, Charles, Philip D., Finelli, Mattéa J., Scott, Connor, Kessler, Benedikt M., Fischer, Roman, Ansorge, Olaf, Gray, Elizabeth, Talbot, Kevin, Turner, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412074/ https://www.ncbi.nlm.nih.gov/pubmed/33300249 http://dx.doi.org/10.1111/bpa.12923

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