Neuroblastoma: A Case of Massive Hepatomegaly

Neuroblastoma is the most common embryonal tumor of childhood and has a variable presentation. Stage 4S neuroblastoma, described as a localized primary tumor in an infant with metastasis to skin, liver, or bone marrow, is an exception to the poor prognosis seen in widespread metastasis of neuroblast...

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Autores principales: Ali, Qamar, Bilal, Muhammad Ibraiz, Ansari, Fawwad A, Gondal, Muhammad Umer Riaz, Arif, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412194/
https://www.ncbi.nlm.nih.gov/pubmed/34513362
http://dx.doi.org/10.7759/cureus.16731
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author Ali, Qamar
Bilal, Muhammad Ibraiz
Ansari, Fawwad A
Gondal, Muhammad Umer Riaz
Arif, Adnan
author_facet Ali, Qamar
Bilal, Muhammad Ibraiz
Ansari, Fawwad A
Gondal, Muhammad Umer Riaz
Arif, Adnan
author_sort Ali, Qamar
collection PubMed
description Neuroblastoma is the most common embryonal tumor of childhood and has a variable presentation. Stage 4S neuroblastoma, described as a localized primary tumor in an infant with metastasis to skin, liver, or bone marrow, is an exception to the poor prognosis seen in widespread metastasis of neuroblastoma. Survival in infants with this stage of the disease is over 90%. Stage 4S with massive liver involvement, however, confers a poor prognosis. We need more research on the optimum treatment modality for patients with Stage 4S disease and massive hepatomegaly to improve patient outcomes.
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spelling pubmed-84121942021-09-09 Neuroblastoma: A Case of Massive Hepatomegaly Ali, Qamar Bilal, Muhammad Ibraiz Ansari, Fawwad A Gondal, Muhammad Umer Riaz Arif, Adnan Cureus Pediatrics Neuroblastoma is the most common embryonal tumor of childhood and has a variable presentation. Stage 4S neuroblastoma, described as a localized primary tumor in an infant with metastasis to skin, liver, or bone marrow, is an exception to the poor prognosis seen in widespread metastasis of neuroblastoma. Survival in infants with this stage of the disease is over 90%. Stage 4S with massive liver involvement, however, confers a poor prognosis. We need more research on the optimum treatment modality for patients with Stage 4S disease and massive hepatomegaly to improve patient outcomes. Cureus 2021-07-29 /pmc/articles/PMC8412194/ /pubmed/34513362 http://dx.doi.org/10.7759/cureus.16731 Text en Copyright © 2021, Ali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Ali, Qamar
Bilal, Muhammad Ibraiz
Ansari, Fawwad A
Gondal, Muhammad Umer Riaz
Arif, Adnan
Neuroblastoma: A Case of Massive Hepatomegaly
title Neuroblastoma: A Case of Massive Hepatomegaly
title_full Neuroblastoma: A Case of Massive Hepatomegaly
title_fullStr Neuroblastoma: A Case of Massive Hepatomegaly
title_full_unstemmed Neuroblastoma: A Case of Massive Hepatomegaly
title_short Neuroblastoma: A Case of Massive Hepatomegaly
title_sort neuroblastoma: a case of massive hepatomegaly
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412194/
https://www.ncbi.nlm.nih.gov/pubmed/34513362
http://dx.doi.org/10.7759/cureus.16731
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AT ansarifawwada neuroblastomaacaseofmassivehepatomegaly
AT gondalmuhammadumerriaz neuroblastomaacaseofmassivehepatomegaly
AT arifadnan neuroblastomaacaseofmassivehepatomegaly

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