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Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines
Self-amplifying RNA (saRNA) is a next-generation vaccine platform, but like all nucleic acids, requires a delivery vehicle to promote cellular uptake and protect the saRNA from degradation. To date, delivery platforms for saRNA have included lipid nanoparticles (LNP), polyplexes and cationic nanoemu...
Autores principales: | Blakney, Anna K., McKay, Paul F., Hu, Kai, Samnuan, Karnyart, Jain, Nikita, Brown, Andrew, Thomas, Anitha, Rogers, Paul, Polra, Krunal, Sallah, Hadijatou, Yeow, Jonathan, Zhu, Yunqing, Stevens, Molly M., Geall, Andrew, Shattock, Robin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412240/ https://www.ncbi.nlm.nih.gov/pubmed/34418521 http://dx.doi.org/10.1016/j.jconrel.2021.08.029 |
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