Cargando…
Risk factors associated with the development of delirium in general ICU patients. A prospective observational study
OBJECTIVE: We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. MATERIAL AND METHODS: Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two group...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412262/ https://www.ncbi.nlm.nih.gov/pubmed/34473734 http://dx.doi.org/10.1371/journal.pone.0255522 |
_version_ | 1783747414894575616 |
---|---|
author | Lobo-Valbuena, Beatriz Gordo, Federico Abella, Ana Garcia-Manzanedo, Sofía Garcia-Arias, Maria-Mercedes Torrejón, Inés Varillas-Delgado, David Molina, Rosario |
author_facet | Lobo-Valbuena, Beatriz Gordo, Federico Abella, Ana Garcia-Manzanedo, Sofía Garcia-Arias, Maria-Mercedes Torrejón, Inés Varillas-Delgado, David Molina, Rosario |
author_sort | Lobo-Valbuena, Beatriz |
collection | PubMed |
description | OBJECTIVE: We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. MATERIAL AND METHODS: Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations. RESULTS: 1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9–8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3–3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission. CONCLUSIONS: The highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care. |
format | Online Article Text |
id | pubmed-8412262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-84122622021-09-03 Risk factors associated with the development of delirium in general ICU patients. A prospective observational study Lobo-Valbuena, Beatriz Gordo, Federico Abella, Ana Garcia-Manzanedo, Sofía Garcia-Arias, Maria-Mercedes Torrejón, Inés Varillas-Delgado, David Molina, Rosario PLoS One Research Article OBJECTIVE: We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. MATERIAL AND METHODS: Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations. RESULTS: 1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9–8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3–3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission. CONCLUSIONS: The highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care. Public Library of Science 2021-09-02 /pmc/articles/PMC8412262/ /pubmed/34473734 http://dx.doi.org/10.1371/journal.pone.0255522 Text en © 2021 Lobo-Valbuena et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Lobo-Valbuena, Beatriz Gordo, Federico Abella, Ana Garcia-Manzanedo, Sofía Garcia-Arias, Maria-Mercedes Torrejón, Inés Varillas-Delgado, David Molina, Rosario Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title | Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title_full | Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title_fullStr | Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title_full_unstemmed | Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title_short | Risk factors associated with the development of delirium in general ICU patients. A prospective observational study |
title_sort | risk factors associated with the development of delirium in general icu patients. a prospective observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412262/ https://www.ncbi.nlm.nih.gov/pubmed/34473734 http://dx.doi.org/10.1371/journal.pone.0255522 |
work_keys_str_mv | AT lobovalbuenabeatriz riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT gordofederico riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT abellaana riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT garciamanzanedosofia riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT garciaariasmariamercedes riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT torrejonines riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT varillasdelgadodavid riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy AT molinarosario riskfactorsassociatedwiththedevelopmentofdeliriumingeneralicupatientsaprospectiveobservationalstudy |