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Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale

Digestive Chagas disease (DCD) is an enteric neuropathy caused by Trypanosoma cruzi infection. The mechanism of pathogenesis is poorly understood and the lack of a robust, predictive animal model has held back research. We screened a series of mouse models using gastrointestinal tracer assays and in...

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Detalles Bibliográficos
Autores principales: Khan, Archie A., Langston, Harry C., Costa, Fernanda C., Olmo, Francisco, Taylor, Martin C., McCann, Conor J., Kelly, John M., Lewis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412264/
https://www.ncbi.nlm.nih.gov/pubmed/34424944
http://dx.doi.org/10.1371/journal.ppat.1009864