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Differential impact of clinicopathological risk factors within the 2 largest ProMisE molecular subgroups of endometrial carcinoma

OBJECTIVE: To assess whether the prognostic impact of conventional risk factors and ancillary biomarkers differs across the 2 largest ProMisE molecular subgroups of endometrial carcinoma (EC). METHODS: Direct sequencing of POLE exonuclease domain hot spots and immunohistochemistry for MLH1, PMS2, MS...

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Detalles Bibliográficos
Autores principales: Pasanen, Annukka, Loukovaara, Mikko, Ahvenainen, Terhi, Vahteristo, Pia, Bützow, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412344/
https://www.ncbi.nlm.nih.gov/pubmed/34473724
http://dx.doi.org/10.1371/journal.pone.0253472

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