Cargando…
RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility
piRNAs are small non-coding RNAs that guide the silencing of transposons and other targets in animal gonads. In Drosophila female germline, many piRNA source loci dubbed “piRNA clusters” lack hallmarks of active genes and exploit an alternative path for transcription, which relies on the Rhino-Deadl...
Autores principales: | Chen, Peiwei, Luo, Yicheng, Aravin, Alexei A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412364/ https://www.ncbi.nlm.nih.gov/pubmed/34473737 http://dx.doi.org/10.1371/journal.pgen.1009591 |
Ejemplares similares
-
To be or not to be a piRNA: genomic origin and processing of piRNAs
por: Le Thomas, Adrien, et al.
Publicado: (2014) -
piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline
por: Chen, Peiwei, et al.
Publicado: (2021) -
The piRNA pathway is developmentally regulated during spermatogenesis in Drosophila
por: Quénerch'du, Emilie, et al.
Publicado: (2016) -
Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
por: Le Thomas, Adrien, et al.
Publicado: (2014) -
A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila
por: Venkei, Zsolt G., et al.
Publicado: (2023)