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Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells

BACKGROUND AND AIM: As a multiple tyrosine kinase inhibitor, sorafenib is widely used to treat hepatocellular carcinoma (HCC), but patients frequently face resistance problems. Because the mechanism controlling sorafenib-resistance is not well understood, this study focused on the connection between...

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Detalles Bibliográficos
Autores principales:	Gao, Luping, Morine, Yuji, Yamada, Shinichiro, Saito, Yu, Ikemoto, Tetsuya, Tokuda, Kazunori, Takasu, Chie, Miyazaki, Katsuki, Shimada, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412368/ https://www.ncbi.nlm.nih.gov/pubmed/34473785 http://dx.doi.org/10.1371/journal.pone.0256755

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