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L-Asparaginase-Induced Hepatotoxicity Treated Successfully With L-Carnitine and Vitamin B Infusion

Asparaginase plays an integral role in chemotherapy for acute lymphoblastic leukemia (ALL). We present a 69-year old woman with refractory ALL, who developed asparaginase-induced hepatotoxicity and cholangiopathy after starting intravenous PEG-L-asparaginase-based chemotherapy. The patient was ultim...

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Detalles Bibliográficos
Autores principales: Lee, Christina, Leventhal, Thomas M, Anugwom, Chimaobi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412850/
https://www.ncbi.nlm.nih.gov/pubmed/34513489
http://dx.doi.org/10.7759/cureus.16917