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Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications
[Image: see text] Since the approval of three hydroxamic acid-based HDAC inhibitors as anticancer drugs, such functional groups acquired even more notoriety in synthetic medicinal chemistry. The ability of hydroxamic acids (HAs) to chelate metal ions makes this moiety an attractive metal binding gro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412920/ https://www.ncbi.nlm.nih.gov/pubmed/34497879 http://dx.doi.org/10.1021/acsomega.1c03628 |