Cargando…

MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes

A relationship between excess epicardial adipose tissue (EAT) and the risk of atrial fibrillation (AF) has been reported. Browning of EAT may be a novel approach for the prevention or treatment of AF by attenuating atrial fibrosis. Previous studies have identified microRNA-21 (miR-21) as a regulator...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Jian-an, Lin, Hao, Yu, Jian-ying, Zhang, Hui-li, Zhang, Jun-feng, Wang, Chang-qian, Gu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413063/ https://www.ncbi.nlm.nih.gov/pubmed/34484568 http://dx.doi.org/10.1155/2021/9987219

Ejemplares similares

Adipose-derived exosomal miR-210/92a cluster inhibits adipose browning via the FGFR-1 signaling pathway in high-altitude hypoxia
por: Zhang, Yifan, et al.
Publicado: (2020)

Circ_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610
por: Guo, Weisheng, et al.
Publicado: (2020)

miR155 deficiency aggravates high‐fat diet‐induced adipose tissue fibrosis in male mice
por: Velázquez, Kandy T., et al.
Publicado: (2017)

Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia
por: Wang, Bo, et al.
Publicado: (2017)

A miR-327–FGF10–FGFR2-mediated autocrine signaling mechanism controls white fat browning
por: Fischer, Carina, et al.
Publicado: (2017)

miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction
por: Hu, Ying, et al.
Publicado: (2020)

CircARVCF Contributes to Cisplatin Resistance in Gastric Cancer by Altering miR-1205 and FGFR1
por: Zhang, Ruirui, et al.
Publicado: (2021)

miR-628 reduces prostate cancer proliferation and invasion via the FGFR2 signaling pathway
por: Chen, Jun, et al.
Publicado: (2019)

Inhibition of miR-25 aggravates diabetic peripheral neuropathy
por: Zhang, Yanzhuo, et al.
Publicado: (2018)

MiR-32-5p aggravates intestinal epithelial cell injury in pediatric enteritis induced by Helicobacter pylori
por: Feng, Jing, et al.
Publicado: (2019)

LncRNA CFRL aggravates cardiac fibrosis by modulating both miR-3113-5p/CTGF and miR-3473d/FN1 axis
por: Cui, Yue, et al.
Publicado: (2023)

Increased Circulating miR-21 Levels Are Associated with Kidney Fibrosis
por: Glowacki, François, et al.
Publicado: (2013)

Expression and predictive value of miR-489 and miR-21 in melanoma metastasis
por: Mo, Hao, et al.
Publicado: (2019)

Urinary miR-21 as a potential biomarker of hypertensive kidney injury and fibrosis
por: Chen, Congcong, et al.
Publicado: (2017)

MiR-21 Simultaneously Regulates ERK1 Signaling in HSC Activation and Hepatocyte EMT in Hepatic Fibrosis
por: Zhao, Juan, et al.
Publicado: (2014)

Twelve-month kinetics of circulating fibrosis-linked microRNAs (miR-21, miR-29, miR-30, and miR-133a) and the relationship with extracellular matrix fibrosis in dilated cardiomyopathy
por: Rubiś, Paweł, et al.
Publicado: (2019)

Considering Exosomal miR-21 as a Biomarker for Cancer
por: Shi, Jian
Publicado: (2016)

MiR-106a aggravates sepsis-induced acute kidney injury by targeting THBS2 in mice model
por: Shen, Yezhou, et al.
Publicado: (2019)

miR-24-3p/FGFR3 Signaling as a Novel Axis Is Involved in Epithelial-Mesenchymal Transition and Regulates Lung Adenocarcinoma Progression
por: Jing, Pengyu, et al.
Publicado: (2018)

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
por: Liu, Gang, et al.
Publicado: (2010)

TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation
por: Loboda, Agnieszka, et al.
Publicado: (2016)

Effect of miR-499-5p/SOX6 axis on atrial fibrosis in rats with atrial fibrillation
por: Han, Xinyuan, et al.
Publicado: (2023)

MiR‐503 suppresses fibroblast activation and myofibroblast differentiation by targeting VEGFA and FGFR1 in silica‐induced pulmonary fibrosis
por: Wu, Qiuyun, et al.
Publicado: (2020)

Effects of miR-21 on proliferation and apoptosis in human gastric adenocarcinoma cells
por: Gu, Jun-Bao, et al.
Publicado: (2018)

miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity
por: Pan, Jian-An, et al.
Publicado: (2019)

Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer
por: Yang, Ying, et al.
Publicado: (2019)

Plasma miR-145, miR-20a, miR-21 and miR-223 as novel biomarkers for screening early-stage non-small cell lung cancer
por: Zhang, Hui, et al.
Publicado: (2017)

miR‐640 aggravates intervertebral disc degeneration via NF‐κB and WNT signalling pathway
por: Dong, Wengang, et al.
Publicado: (2019)

miR-802 inhibits the aggressive behaviors of non-small cell lung cancer cells by directly targeting FGFR1
por: Zhang, Jiexia, et al.
Publicado: (2022)

miR−21 and NT-proBNP Correlate with Echocardiographic Parameters of Atrial Dysfunction and Predict Atrial Fibrillation
por: Sieweke, Jan-Thorben, et al.
Publicado: (2020)

NF-κB downstream miR-1262 disturbs colon cancer cell malignant behaviors by targeting FGFR1: NF-κB/miR-1262/FGFR1 modulates colon cancer oncogenesis
por: Zhang, Weilin, et al.
Publicado: (2023)

Fibroblast Growth Factor 21 and Browning of White Adipose Tissue
por: Cuevas-Ramos, Daniel, et al.
Publicado: (2019)

miR-328-3p, a Predictor of Stroke, Aggravates the Cerebral Ischemia-Reperfusion Injury
por: Wang, Shun, et al.
Publicado: (2021)

miR-20a-5p/TGFBR2 Axis Affects Pro-inflammatory Macrophages and Aggravates Liver Fibrosis
por: Fu, Xiutao, et al.
Publicado: (2020)

Circular RNA circEIF4G2 aggravates renal fibrosis in diabetic nephropathy by sponging miR‐218
por: Xu, Bojin, et al.
Publicado: (2020)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

miR-217-5p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2
por: Zhu, Menghai, et al.
Publicado: (2020)

miR-21 in Human Cardiomyopathies
por: Surina,, et al.
Publicado: (2021)

MiR-21 and let-7 cooperation in the regulation of lung cancer
por: Bai, Jinquan, et al.
Publicado: (2022)

Serum levels of miR-21-5p and miR-339-5p associate with occupational trichloroethylene hypersensitivity syndrome
por: Liu, Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e0fnsl63suekngfs6qqapgorm5