Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept

INTRODUCTION: Tolerance (TOL) and physical dependence (PD) constitute important limitations of opioid therapy. The aim of our study was to validate research tools to investigate TOL and PD and to characterize the interactions between opioid (OR) and cannabinoid (CB) receptors in these processes in t...

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Detalles Bibliográficos
Autores principales: Szymaszkiewicz, Agata, Świerczyński, Mikołaj, Talar, Marcin, Polepally, Prabhakar Reddy, Zjawiony, Jordan K., Fichna, Jakub, Zielińska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Special Issue: Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413198/
https://www.ncbi.nlm.nih.gov/pubmed/34133018
http://dx.doi.org/10.1007/s43440-021-00291-7

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