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Serum protein electrophoretic pattern in piglets during the early postnatal period

The pattern of serum proteins, the typical features of the electrophoretogram in newborn piglets and during their postnatal development is not completely described. Therefore, the aim of this study was to characterize the changes in serum protein electrophoretic pattern and features of the electroph...

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Autores principales: Tóthová, Csilla, Link, Robert, Kyzeková, Petronela, Nagy, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413273/
https://www.ncbi.nlm.nih.gov/pubmed/34475487
http://dx.doi.org/10.1038/s41598-021-96957-6
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author Tóthová, Csilla
Link, Robert
Kyzeková, Petronela
Nagy, Oskar
author_facet Tóthová, Csilla
Link, Robert
Kyzeková, Petronela
Nagy, Oskar
author_sort Tóthová, Csilla
collection PubMed
description The pattern of serum proteins, the typical features of the electrophoretogram in newborn piglets and during their postnatal development is not completely described. Therefore, the aim of this study was to characterize the changes in serum protein electrophoretic pattern and features of the electrophoretograms during the early postnatal period. Significant changes during the monitored period were found in all evaluated parameters (P < 0.001). The most marked changes were observed mainly in the period before weaning. The concentrations of total proteins, albumin and γ-globulins were before colostrum intake low, γ-globulins represented the smallest proportion of protein fractions. The proportion of α(1)-globulins was after birth a dominant protein fraction. Significant increase of total proteins, α(2)-, β- and γ-globulins and decrease of α(1)-globulins was found 2 days after colostrum intake. The albumin and A/G values increased after birth gradually until weaning. After weaning a significant changes were found in absolute concentrations of total protein and albumin, and in relative values of β-globulin fractions. Presented results showed marked developmental alterations in the serum protein pattern in piglets along with the age. The study also brings new knowledge in the field of description of typical features of electrophoretograms in the observed period of piglet’s life.
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spelling pubmed-84132732021-09-03 Serum protein electrophoretic pattern in piglets during the early postnatal period Tóthová, Csilla Link, Robert Kyzeková, Petronela Nagy, Oskar Sci Rep Article The pattern of serum proteins, the typical features of the electrophoretogram in newborn piglets and during their postnatal development is not completely described. Therefore, the aim of this study was to characterize the changes in serum protein electrophoretic pattern and features of the electrophoretograms during the early postnatal period. Significant changes during the monitored period were found in all evaluated parameters (P < 0.001). The most marked changes were observed mainly in the period before weaning. The concentrations of total proteins, albumin and γ-globulins were before colostrum intake low, γ-globulins represented the smallest proportion of protein fractions. The proportion of α(1)-globulins was after birth a dominant protein fraction. Significant increase of total proteins, α(2)-, β- and γ-globulins and decrease of α(1)-globulins was found 2 days after colostrum intake. The albumin and A/G values increased after birth gradually until weaning. After weaning a significant changes were found in absolute concentrations of total protein and albumin, and in relative values of β-globulin fractions. Presented results showed marked developmental alterations in the serum protein pattern in piglets along with the age. The study also brings new knowledge in the field of description of typical features of electrophoretograms in the observed period of piglet’s life. Nature Publishing Group UK 2021-09-02 /pmc/articles/PMC8413273/ /pubmed/34475487 http://dx.doi.org/10.1038/s41598-021-96957-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Tóthová, Csilla
Link, Robert
Kyzeková, Petronela
Nagy, Oskar
Serum protein electrophoretic pattern in piglets during the early postnatal period
title Serum protein electrophoretic pattern in piglets during the early postnatal period
title_full Serum protein electrophoretic pattern in piglets during the early postnatal period
title_fullStr Serum protein electrophoretic pattern in piglets during the early postnatal period
title_full_unstemmed Serum protein electrophoretic pattern in piglets during the early postnatal period
title_short Serum protein electrophoretic pattern in piglets during the early postnatal period
title_sort serum protein electrophoretic pattern in piglets during the early postnatal period
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413273/
https://www.ncbi.nlm.nih.gov/pubmed/34475487
http://dx.doi.org/10.1038/s41598-021-96957-6
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