Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links

Human PrimPol belongs to the archaeo-eukaryotic primase superfamily of primases and is involved in de novo DNA synthesis downstream of blocking DNA lesions and non-B DNA structures. PrimPol possesses both DNA/RNA primase and DNA polymerase activities, and also bypasses a number of DNA lesions in vit...

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Detalles Bibliográficos
Autores principales: Boldinova, Elizaveta O., Yudkina, Anna V., Shilkin, Evgeniy S., Gagarinskaya, Diana I., Baranovskiy, Andrey G., Tahirov, Tahir H., Zharkov, Dmitry O., Makarova, Alena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413282/
https://www.ncbi.nlm.nih.gov/pubmed/34475447
http://dx.doi.org/10.1038/s41598-021-96692-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413282/
https://www.ncbi.nlm.nih.gov/pubmed/34475447
http://dx.doi.org/10.1038/s41598-021-96692-y

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