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A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models

Detalles Bibliográficos
Autores principales: Fan, Jiansheng, Zhuang, Xinlei, Yang, Xiaoyue, Xu, Yingchun, Zhou, Zhan, Pan, Liqiang, Chen, Shuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413295/
https://www.ncbi.nlm.nih.gov/pubmed/34475375
http://dx.doi.org/10.1038/s41392-021-00666-5
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author Fan, Jiansheng
Zhuang, Xinlei
Yang, Xiaoyue
Xu, Yingchun
Zhou, Zhan
Pan, Liqiang
Chen, Shuqing
author_facet Fan, Jiansheng
Zhuang, Xinlei
Yang, Xiaoyue
Xu, Yingchun
Zhou, Zhan
Pan, Liqiang
Chen, Shuqing
author_sort Fan, Jiansheng
collection PubMed
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spelling pubmed-84132952021-09-22 A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models Fan, Jiansheng Zhuang, Xinlei Yang, Xiaoyue Xu, Yingchun Zhou, Zhan Pan, Liqiang Chen, Shuqing Signal Transduct Target Ther Letter Nature Publishing Group UK 2021-09-03 /pmc/articles/PMC8413295/ /pubmed/34475375 http://dx.doi.org/10.1038/s41392-021-00666-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter
Fan, Jiansheng
Zhuang, Xinlei
Yang, Xiaoyue
Xu, Yingchun
Zhou, Zhan
Pan, Liqiang
Chen, Shuqing
A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title_full A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title_fullStr A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title_full_unstemmed A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title_short A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
title_sort multivalent biparatopic egfr-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413295/
https://www.ncbi.nlm.nih.gov/pubmed/34475375
http://dx.doi.org/10.1038/s41392-021-00666-5
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