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SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3

The prevalence of SARS-CoV-2 is a great threat to global public health. However, the relationship between the viral pathogen SARS-CoV-2 and host innate immunity has not yet been well studied. The genome of SARS-CoV-2 encodes a viral protease called 3C-like protease. This protease is responsible for...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenwen, Ma, Zhenling, Wu, Yaru, Shi, Xixi, Zhang, Yanyan, Zhang, Min, Zhang, Menghao, Wang, Lei, Liu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413301/ https://www.ncbi.nlm.nih.gov/pubmed/34509038 http://dx.doi.org/10.1016/j.cyto.2021.155697

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