The shared genetic architecture between epidemiological and behavioral traits with lung cancer

The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to identify novel phenotypes associated with lung cancer using cross-trait linkage disequilibrium score regression (LDSR). We measured pairwise genetic correlation (r(g)) and SNP heritability (h(2)) between 347 t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pettit, Rowland W., Byun, Jinyoung, Han, Younghun, Ostrom, Quinn T., Edelson, Jacob, Walsh, Kyle M., Bondy, Melissa L., Hung, Rayjean J., McKay, James D., Amos, Christopher I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413319/
https://www.ncbi.nlm.nih.gov/pubmed/34475455
http://dx.doi.org/10.1038/s41598-021-96685-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413319/
https://www.ncbi.nlm.nih.gov/pubmed/34475455
http://dx.doi.org/10.1038/s41598-021-96685-x

Ejemplares similares