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The shared genetic architecture between epidemiological and behavioral traits with lung cancer
The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to identify novel phenotypes associated with lung cancer using cross-trait linkage disequilibrium score regression (LDSR). We measured pairwise genetic correlation (r(g)) and SNP heritability (h(2)) between 347 t...
Autores principales: | Pettit, Rowland W., Byun, Jinyoung, Han, Younghun, Ostrom, Quinn T., Edelson, Jacob, Walsh, Kyle M., Bondy, Melissa L., Hung, Rayjean J., McKay, James D., Amos, Christopher I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413319/ https://www.ncbi.nlm.nih.gov/pubmed/34475455 http://dx.doi.org/10.1038/s41598-021-96685-x |
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