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Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission

The function of the amyloid precursor protein (APP) is not fully understood, but its cleavage product amyloid beta (Aβ) together with neurofibrillary tangles constitute the hallmarks of Alzheimer’s disease (AD). Yet, imbalance of excitatory and inhibitory neurotransmission accompanied by loss of syn...

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Detalles Bibliográficos
Autores principales:	Kreis, Anna, Desloovere, Jana, Suelves, Nuria, Pierrot, Nathalie, Yerna, Xavier, Issa, Farah, Schakman, Olivier, Gualdani, Roberta, de Clippele, Marie, Tajeddine, Nicolas, Kienlen-Campard, Pascal, Raedt, Robrecht, Octave, Jean-Noël, Gailly, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413381/ https://www.ncbi.nlm.nih.gov/pubmed/34475508 http://dx.doi.org/10.1038/s41598-021-97144-3

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