Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity

The wake-active orexin system plays a central role in the dynamic regulation of glucose homeostasis. Here we show orexin receptor type 1 and 2 are predominantly expressed in dorsal raphe nucleus-dorsal and -ventral, respectively. Serotonergic neurons in ventral median raphe nucleus and raphe pallidu...

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Detalles Bibliográficos
Autores principales: Xiao, Xing, Yeghiazaryan, Gagik, Hess, Simon, Klemm, Paul, Sieben, Anna, Kleinridders, André, Morgan, Donald A., Wunderlich, F. Thomas, Rahmouni, Kamal, Kong, Dong, Scammell, Thomas E., Lowell, Bradford B., Kloppenburg, Peter, Brüning, Jens C., Hausen, A. Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413382/
https://www.ncbi.nlm.nih.gov/pubmed/34475397
http://dx.doi.org/10.1038/s41467-021-25380-2

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