Cargando…

Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification

During hematopoietic development, definitive hematopoietic cells are derived from hemogenic endothelial (HE) cells through a process known as endothelial to hematopoietic transition (EHT). During EHT, transitioning cells proliferate and undergo progressive changes in gene expression culminating in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oburoglu, Leal, Mansell, Els, Woods, Niels-Bjarne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413451/ https://www.ncbi.nlm.nih.gov/pubmed/34475502 http://dx.doi.org/10.1038/s41598-021-97194-7

Ejemplares similares

Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
por: Oburoglu, Leal, et al.
Publicado: (2021)

Opening the window for endothelial-to-hematopoietic transition
por: Samarakkody, Ann Sanoji, et al.
Publicado: (2021)

Autophagy and Its Lineage-Specific Roles in the Hematopoietic System
por: Hasan, Kazi Md Mahmudul, et al.
Publicado: (2023)

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition
por: Kang, HyunJun, et al.
Publicado: (2018)

The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
por: Azzoni, Emanuele, et al.
Publicado: (2021)

S100A6 is a critical regulator of hematopoietic stem cells
por: Grahn, Tan Hooi Min, et al.
Publicado: (2020)

New insights into the regulation by RUNX1 and GFI1(s) proteins of the endothelial to hematopoietic transition generating primordial hematopoietic cells
por: Thambyrajah, Roshana, et al.
Publicado: (2016)

Retinoic Acid Regulates Hematopoietic Development from Human Pluripotent Stem Cells
por: Rönn, Roger E., et al.
Publicado: (2015)

Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
por: Roy, Anindita, et al.
Publicado: (2021)

Runx1 is required for the endothelial to hematopoietic cell transition but not thereafter
por: Chen, Michael J., et al.
Publicado: (2009)

Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition
por: Serina Secanechia, Yasmin Natalia, et al.
Publicado: (2022)

Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors
por: Klein, Fabian, et al.
Publicado: (2022)

Nupr1 Negatively Regulates Endothelial to Hematopoietic Transition in the Aorta‐Gonad‐Mesonephros Region
por: Wang, Haizhen, et al.
Publicado: (2023)

Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence
por: Iizuka, Kazuhide, et al.
Publicado: (2016)

The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia
por: Rowe, R. Grant, et al.
Publicado: (2019)

Exogenous endothelial cells as accelerators of hematopoietic reconstitution
por: Mizer, J Christopher, et al.
Publicado: (2012)

Metabolic Regulation of Hematopoietic Stem Cells
por: Morganti, Claudia, et al.
Publicado: (2022)

Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region
por: Rybtsov, Stanislav, et al.
Publicado: (2011)

Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC
por: Wang, Ning, et al.
Publicado: (2022)

Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition
por: Koyunlar, Cansu, et al.
Publicado: (2023)

Efficacy of parenteral glutamine supplementation in adult hematopoietic stem cell transplantation patients
por: Cho, Yun Kyung, et al.
Publicado: (2019)

Prospective identification of hematopoietic lineage choice by deep learning
por: Buggenthin, Felix, et al.
Publicado: (2017)

A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells
por: Li, Yapu, et al.
Publicado: (2020)

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
por: Warsi, Sarah, et al.
Publicado: (2022)

Specific Marking of hESCs-Derived Hematopoietic Lineage by WAS-Promoter Driven Lentiviral Vectors
por: Muñoz, Pilar, et al.
Publicado: (2012)

Differential Adhesion Molecule Expression during Murine Embryonic Stem Cell Commitment to the Hematopoietic and Endothelial Lineages
por: Stankovich, Basha L., et al.
Publicado: (2011)

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches
por: Wu, Joy Y, et al.
Publicado: (2009)

MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1
por: Wang, Mengge, et al.
Publicado: (2018)

Perspective: Biophysical regulation of cancerous and normal blood cell lineages in hematopoietic malignancies
por: Wong, Sing Wan, et al.
Publicado: (2018)

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity
por: Wang, Jueqiong, et al.
Publicado: (2021)

Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation
por: Saxena, Shobhit, et al.
Publicado: (2016)

Endothelial Dysfunction in Hematopoietic Cell Transplantation
por: Palomo, Marta, et al.
Publicado: (2019)

Intra-Aortic Clusters Undergo Endothelial to Hematopoietic Phenotypic Transition during Early Embryogenesis
por: Mizuochi, Chiyo, et al.
Publicado: (2012)

Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation
por: Georgolopoulos, Grigorios, et al.
Publicado: (2021)

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
por: Wahlestedt, Martin, et al.
Publicado: (2017)

Two Hemocyte Lineages Exist in Silkworm Larval Hematopoietic Organ
por: Nakahara, Yuichi, et al.
Publicado: (2010)

Lineage-Specific Chimerism and Outcome After Hematopoietic Stem Cell Transplantation for DOCK8 Deficiency
por: Raedler, Johannes, et al.
Publicado: (2021)

Correction to: MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1
por: Wang, Mengge, et al.
Publicado: (2020)

Making Blood from the Vessel: Extrinsic and Environmental Cues Guiding the Endothelial-to-Hematopoietic Transition
por: Sugden, Wade W., et al.
Publicado: (2021)

Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
por: Lai, Anne Y., et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_e1qul9jfqsrl56o7nb4ran4g2t