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mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD

Mesenchymal stromal cells (MSCs) have shown significant heterogeneity in terms of therapeutic efficacy for inflammatory bowel disease (IBD) treatment, which may be due to an insufficient number of MSCs homing to the damaged tissue of the colon. Engineering MSCs with specific chemokine receptors can...

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Detalles Bibliográficos
Autores principales: Li, Qiaojia, Lian, Yufan, Deng, Yiwen, Chen, Jieying, Wu, Tao, Lai, Xinqiang, Zheng, Bowen, Qiu, Chen, Peng, Yanwen, Li, Weiqiang, Xiang, Andy Peng, Zhang, Xiaoran, Ren, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413681/
https://www.ncbi.nlm.nih.gov/pubmed/34513306
http://dx.doi.org/10.1016/j.omtn.2021.07.009