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Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load

BACKGROUND: Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs) is evident, it is unknown whether the first res...

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Detalles Bibliográficos
Autores principales:	Reijm, Sanne, Kissel, Theresa, Stoeken-Rijsbergen, Gerrie, Slot, Linda M., Wortel, Corrie M., van Dooren, Hugo J., Levarht, Nivine E. W., Kampstra, Arieke S. B., Derksen, Veerle F. A. M., Heer, Pleuni Ooijevaar-de, Bang, Holger, Drijfhout, Jan W., Trouw, Leendert A., Huizinga, Tom W. J., Rispens, Theo, Scherer, Hans U., Toes, René E. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413699/ https://www.ncbi.nlm.nih.gov/pubmed/34479638 http://dx.doi.org/10.1186/s13075-021-02609-5

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